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New Arrival: Olmedip, A Powerful, Safe & Effective Option for hard-to-treat hypertensive patients


 

Olmedip is the combination of Amlodipine, a dihydropyridine calcium channel blocker (CCB), with Olmesartan Medoxomil, an angiotensin receptor blocker (ARB).

 

Amlodipine, a Calcium channel blocker decreases the entry of calcium ions into cells by blocking L-type calcium channels, leading to relaxation of arterial smooth muscle, peripheral vasodilation, and lowered BP. Olmesartan Medoxomil is a prodrug that undergoes ester hydrolysis in the GI tract to form its active metabolite Olmesartan. Olmesartan, an Angiotensin receptor blockers acts by selectively binding to the AT1 receptor, blocking the effects of angiotensin II, and therefore suppressing vasoconstriction and other adverse CV effects of angiotensin II. It is available as 5/20 and 5/40 mg tablet.