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New arrival: Taglimet 50/500 Tablet & Taglimet 50/1000 Tablet
lTaglimet is a preparation of Sitagliptin 50 mg and Metformin 500 mg & Sitagliptin 50 mg and Metformin 1000 mg tablet. Sitagliptin phosphate is an orally-active, potent, and highly selective inhibitor of the dipeptidyl peptidase 4 (DPP-4) enzyme for the treatment of type 2 diabetes. The DPP-4 inhibitors are a class of agents that act as incretin enhancers. Metformin improves glucose tolerance in patients with type 2 diabetes, lowering both basal and postprandial plasma glucose. Metformin decreases hepatic glucose production, decreases intestinal absorption of glucose, and improves insulin sensitivity by increasing peripheral glucose uptake and utilization.
Combination of Sitagliptin and Metformin indicated as an adjunct to diet and exercise to improve glycaemic control.