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|NAME||STRENGTH||PACK SIZE||DOSAGE FORM|
|Ebamine||5 mg/5 ml||30 ml||Syrup|
|Ebamine||5 mg/5 ml||50 ml||Syrup|
Ebastine is a long-acting and selective H1-histamine receptor antagonist. After repeated administration, inhibition of peripheral receptors remains at a constant level. Ebastine is rapidly absorbed and undergoes extensive first pass metabolism following oral administration. Ebastine is almost totally converted to the pharmacologically active acid metabolite, carebastine.
Ebamine Tablet: Each film-coated tablet contains Ebastine BP 10 mg. Ebamine 30 ml & 50 ml Syrup: Each 5 ml syrup contains Ebastine BP 5 mg.
Indications And Uses
Ebastine is indicated for the symptomatic treatment of: • Seasonal and Perennial Allergic Rhinitis • Chronic Idiopathic Urticaria
Dosage And Administration
Tablet: Adults (more than 12 years of age): 10 mg (one tablet) once daily. Children (6-12 years of age): 5 mg (half tablet) once daily. Syrup: Children (2-5 years of age): 2.5 ml once daily (upto 5 ml in severe cases such as Perennial Allergic Rhinitis). Children (6-12 years of age): 5 ml once daily (upto 10 ml in severe cases such as Perennial Allergic Rhinitis). Ebastine may be taken with or without food.
The most common side-effects are headache, dry mouth and drowsiness. Less commonly reported side effects include abdominal pain, dyspepsia, nausea and insomnia.
Ebastine in combination with either ketoconazole or erythromycin increase in plasma level of ebastine and prolonged QTc interval. Ebastine does not interact with the pharmacokinetics of theophylline, warfarin, cimetidine, diazepam or alcohol. The sedation effect of alcohol and diazepam may be enhanced.
Store below 30° C at a cool and dry place, away from light. Keep out of reach of children.
Patients with a known hypersensitivity to Ebastine or any of its ingredients.
Ebamine Tablet: Each box contains 3 x 10 tablets in blister pack. Ebamine 30 ml & 50 ml Syrup: Each bottle contains 30 ml & 50 ml Syrup.