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Erythromycin Ethyl Succinate USP
|NAME||STRENGTH||PACK SIZE||DOSAGE FORM|
|Erymex||125 mg/ 5 ml||100 ml||Powder for suspension|
|Erymex 500||500 mg||3X10||Tablet|
Erymex (Erythromycin) is a macrolide antibiotic with bacteriostatic action. It acts by inhibition of protein synthesis by binding 50s ribosomal subunit of susceptible organisms which interferes with bacterial growth & multiplication. It is active against many gram-positive bacteria, some gram-negative bacteria and against mycoplasma and chlamydia.
Erymex 500 Tablet: Each tablet contains Erythromycin 500 mg as Erythromycin Stearate USP. Erymex 100 ml Suspension: Each 5 ml reconstituted suspension contains Erythromycin 125 mg as Erythromycin Ethyl Succinate USP.
Indications And Uses
Erymex is indicated for the prophylaxis & treatment of the following clinical conditions caused by Erythromycin sensitive microorganisms: Upper respiratory tract infection: Tonsillitis, pharyngitis, laryngitis, sinusitis, secondary infection in cold and influenza. Lower respiratory tract infection: Tracheitis, acute and chronic bronchitis, pneumonia (Lobar pneumonia, broncho-pneumonia, primary atypical pneumonia), whooping cough, legionnaries disease. Ear & oral infection: Otitis media & otitis externa, mastoiditis, gingivitis, Vincents angina. Skin & soft tissue infection: Acne vulgaris, erythrasama, boils and carbuncles, impetigo, abscesses, cellulitis. Gastro-intestinal infection: Cholecystitis, Staphylococcal enterocolitis. Veneral infection: Urethritis, syphillis, lymphogranuloma venereum. Other infection: Osteomyelitis, diphtheria, rheumatic fever, whooping cough.
Dosage And Administration
Adult & children over 8 years: The usual dose is 250-500 mg every 6 hours or 0.5-1.0 gm every 12 hours. This may be increased up to 4 gm per day according to the severity of the infection. Children aged 2-8 years: 250 mg every 6 hours or 30-50 mg/kg/day divided into 4 equal doses. In severe cases this dose may be doubled. Infants and children up to 2 years: 500 mg daily in divided doses or 30-50 mg/kg/day in divided doses. Dose may be doubled in severe infection.
Erythromycin & its salts are well tolerated & serious side effects are rare. Nausea, gastrointestinal disturbance and allergy may occur.
Caution should be taken when administering it to patients with liver dysfunction or who are currently receiving potentially hepatotoxic drugs.
Use In Pregnancy Lactation
The drug is considered as safer antibiotics. Clinical and laboratory studies have been shown no evidence of teratogenicity or toxicity.
Store in cool and dry place, protect from light. Keep the products out of the reach of children.
It is contraindicated to the patient who has a history of previous hypersensitivity reaction to the drug
Erymex 500 mg Tablet: Each box contains 30 (3x10's) tablets in blister strip. Erymex Dry 100 ml Suspension: Each bottle contains dry powder for 100 ml oral suspension with a measuring spoon.