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Flucloxacillin Sodium BP
|NAME||STRENGTH||PACK SIZE||DOSAGE FORM|
|Sinaflox 250||250 mg||5X10||Capsule|
|Sinaflox 500||500 mg||5X10||Capsule|
|Sinaflox||125 mg/ 5 ml||100 ml||Powder for suspension|
Sinaflox is a preparation of Flucloxacillin. It is active against gram-positive organisms, including penicillinase producing strains.
Sinaflox 250 Capsule: Each capsule contains Flucloxacillin BP 250 mg (as Flucloxacillin Sodium BP). Sinaflox 500 Capsule: Each capsule contains Flucloxacillin BP 500 mg (as Flucloxacillin Sodium BP). Sinaflox Dry Syrup : Each 5 ml contains Flucloxacillin BP 125 mg (as Flucloxacillin Sodium BP).
Indications And Uses
Skin and Soft Tissue Infections: Boils, abscesses, carbuncles, furunculosis,infected wounds, infected burns, protection of skin grafts, otitis media and externa, impetigo. Infected Skin Conditions. Ulcer, eczema and acne. Respiratory Tract Infections: Pneumonia, lung abscess, empyema, sinusitis,pharyngitis, tonsillitis, quinsy. Other infections caused by Flucloxacillin-sensitive organisms such as osteomyelitis, enteritis, endocarditis, urinary tract infection, meningitis, septicaemia. Flucloxacillin is also indicated for use as a prophylactic agent during major surgical procedures where appropriate, for example, cardiothoracic and orthopaedic surgery
Dosage And Administration
Adults (including elderly patients): Oral: 250-500mg three to four times a day. Oral doses should be administered 1 hour before meal Children 2-10 years: Half of adult dose Under 2 years: One fourth of adult dose Children have been given doses of 12.5mg/kg body weight four times a day. Patients with impaired renal function: As common with other penicillins, Flucloxacillin usage in patients with renal impairment does not usually require dosage reduction. However in the presence of severe renal failure (creatinine clearance<10 ml/min) a reduction in dose or an extension of dose interval should be considered. Directions for reconstitution Inclox dry powder for syrup : Add 60 ml (with the help of supplied measuring cup) of boiled and cooled water to the dry mixture in the bottle. For ease of preparation add water to the bottle in two portions. Shake the bottle well after each addition of water until all the powder is in syrup. Note: Shake the bottle well before each use. Keep the bottle tightly closed.
There have been some common side effects of GIT such as nausea, vomiting, diarrhoea, dyspepsia and other minor gastrointestinal disturbances. Besides these rashes, urticaria, purpura, fever, interstitial nephritis, hepatitis and cholestatic jaundice have been reported
Use In Pregnancy Lactation
Use in pregnancy Penicillins are generally considered safe for use in pregnancy. Animal studies with Flucloxacillin have shown no teratogenic effects. Use in lactation Flucloxacillin is excreted in breast milk in trace amounts. Flucloxacillin may be administered during the period of lactation
Flucloxacillin should not be given to penicillin-hypersensitive patients.
Although overdosage problems are unlikely to occur with penicillins, and should be treated symptomatically
Sinaflox 250 Capsule: Box containing 5 x 10 capsules in alu-alu blister pack. Sinaflox 500 Capsule: Box containing 5 x 10 capsules in alu-alu blister pack. Sinaflox Dry Syrup : Bottle containing dry powder for reconstitution 100 ml.