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Tetrasina
Tetracycline HCl BP
| NAME | STRENGTH | PACK SIZE | DOSAGE FORM |
|---|---|---|---|
| Tetrasina 250 | 250 mg | 10X10 | Capsule |
| Tetrasina 500 | 500 mg | 5X10 | Capsule |
Description
Tetrasina (Tetracycline) is a broad-spectrum antibiotic which is bacteriostatic for many bacteria, rickettsiae, chlamydia, mycoplasma and brucella. It exerts its antimicrobial effect by inhibiting protein synthesis. After a single oral dose of Tetracycline peak plasma concentration is attained in 2 to 4 hours. The drug's half-life is in the range of 6 to 9 hours. Because of its enterohepatic circulation, Tetracycline may be present in the blood for a long time after cessation of therapy.
Composition
Tetrasina Capsule: Each capsule contains Tetracycline 250 mg as Tetracycline Hydrochloride BP. Tetrasina 500 Capsule: Each capsule contains Tetracycline 500 mg as Tetracycline Hydrochloride BP.
Indications And Uses
Tetrasina is indicated for the treatment of infection caused by the susceptible organisms. Typical indications include -Ear, nose and throat infection: Sinusitis, tonsilitis, pharyngitis, acute otitis media. Respiratory tract infection: Acute and chronic bronchitis (exacerbation), lobar and bronchopneumonia, atypical pneumonia, lung abscess. Gastro-intestinal tract infection: Amoebic dysentery, bacillary dysentery, enteritis. Hepatic infection: Cholangitis, cholecystitis. Venereal diseases: Gonorrhoea, syphillis (Primary stage). Genito-urinary tract infection: Pyelonephritis, cystitis, urethritis, prostatitis, epididymitis. Rickettsial infection: Typhus fever, spotted fever. Chlamydial infection: Psittacosis, trachoma, non-gonococcal urethritis, chlamydial conjunctivitis, lymphogranuloma venereum. Mycoplasmal infection: (caused by Mycoplasma pneumoniae) other infections: Bacterial endocarditis, sepsis, thrombophlebitis, Bacterial meningitis, whooping cough, brucellosis (in combination with other antimicrobial agents), actinomycosis, anthrax, acne. Tetracycline is also used in the treatment of plague with Streptomycin.
Dosage And Administration
Adult: Usually 250 to 500 mg every 6 hour by mouth. Higher doses up to 3 or 4 gm daily have occasionally been given in resistant case. Gonorrhoea: 500 mg 4 times daily for 7 days. Non-gonococcal urethritis: 500 mg 4 times daily for 7-14 days. Primary, secondary or latent syphilis: 500 mg 4 times daily for 15 days. Acne vulgaris: 500 mg twice daily for 3 months, reduced to 250 mg twice daily for a further 3 months. Children: Tetracycline is not suitable for children under 12 years of age.
Side Effect
Nausea, vomiting, diarrhoea, headache, superinfection with resistant organisms.
Precaution
Tetracycline should be taken either an hour before or 2 hours after meal. The drug should not be administered concurrently with mask, alkali and antacid.
Use In Pregnancy Lactation
Contraindicated in Pregnency and lactation.
Contraindications
Pregnancy and lactation, renal insufficiency, systemic lupus erythematous, history to hypersensitivity.
How Supplied
Tetrasina Capsule: Box contains 100 (10x10's) capsules in Aluminium strip. Tetrasina 500 Capsule: Box contains 50 (10x5's) capsules in Aluminium strip.