Insimet is a preparation of Metformin. It is a biguanide type oral antihyperglycemic drug used in the management of type 2 diabetes. It is available as 500 mg, 850 mg tablet and Insimet XR 500 mg tablet
Linagliptin is an inhibitor of DPP-4, an enzyme that degrades the incretin hormones glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP). Thus, linagliptin increases the concentrations of active incretin hormones, stimulating the release of insulin in a glucose-dependent manner and decreasing the levels of glucagon in the circulation.