It is given orally for the prophylaxis of migraine and for the
prevention of headache attacks during cluster periods. It is not effective in
acute attacks of migraine. Antigrain is indicated in the Prophylactic treatment of recurrent vascular headaches, including classical migraine, common migraine and cluster headache. It is available as (5x10’s) tablets in blister strip and also (3x10’s) TS tablets in blister strip.
Lograin (Tolfenamic acid) is a potent prostaglandin biosynthesis inhibitor. It is an NSAID with anti-inflammatory, analgesic and antipyretic effects. It acts by inhibiting prostaglandin and leukotriene synthesis. It is indicated for the treatment of Acute Migraine. It is available as 200 mg tablet.
Lunarzin (Flunarizine) is the difluorinated derivative of cinnarizine. It is a selective calcium channel antagonist. By reducing excessive transmembrane influx of calcium Lunarzin prevents cellular calcium overload. It does not interfere with normal cellular calcium homeostasis. Lunarzin also has some antihistaminic and sedative properties. It binds at an affinity of 99% to plasma protein.